volatile bool pressed = false;

void isr0() {
  digitalWrite(13, !digitalRead(13));
  pressed = true;
  detachInterrupt(digitalPinToInterrupt(2));
}

void setup() {
  Serial.begin(9600);
  pinMode(2, INPUT_PULLUP);
  pinMode(13, OUTPUT);
  digitalWrite(13, LOW);
  attachInterrupt(digitalPinToInterrupt(2), isr0, FALLING);
}

void loop() {
  static int test;
  if (pressed) {
    delay(1000);
    digitalWrite(13, LOW);
    delay(4000);
    pressed = false;
    attachInterrupt(digitalPinToInterrupt(2), isr0, FALLING);
  } else {
    Serial.println(++test);
    delay(100);
  }
}